inHales Respiratory Simulator

The InHALES (Independent Holistic Air-Liquid Exposure System) is a human-relevant aerosol exposure platform for inhalation toxicology research. It generates configurable breathing profiles with precise control of flow rate, volume, humidity and temperature.

Co-developed with PMI R&D Neuchâtel and published in Toxicology in Vitro (2020), the system was designed to provide a more physiologically relevant alternative to conventional aerosol exposure methods. It has also been integrated with TissUse's HUMIMIC platform for systemic exposure studies.

Specifications

Technical data

Humidity sensor	SHT45-AD1B-R2
Control	Custom PCB with Phidgets industrial I/O

Interface	13.3" AMOLED touchscreen
Profiles	ISO 27427 compatible
Enclosure	Anodized aluminum, Swiss Made

Key Features

What sets the inHales apart

Programmable breathing profiles

Sinusoidal, square, and custom breathing profiles for maximum experimental flexibility in inhalation research.

Integrated humidity sensing

Sensirion SHT45 sensor provides precise humidity and temperature monitoring throughout the respiratory cycle.

Real-time parameter display

Live visualization of all respiratory parameters on the integrated touchscreen HMI during experiments.

Full data traceability

Complete data logging with experiment traceability for regulatory compliance and research documentation.

Video

How InHALES works

Animation: SciAni / PMI Science

Publications

Peer-reviewed research

Steiner S., Herve P., Pak C., Majeed S., Sandoz A., Kuczaj A., Hoeng J. — "Development and testing of a new-generation aerosol exposure system: The independent holistic air-liquid exposure system (InHALES)"

Toxicology in Vitro 67, 2020

Additional poster: HUMIMIC-InHALES — "A Human-Relevant Aerosol Test Platform for Systemic Exposure Studies" (TissUse / PMI Science)

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